Esco Aster

Overview

Esco Aster is a vertically integrated bioinnovation venture accelerator and contract research and manufacturing organization (CRDMO) delivering end-to-end "idea-to-exit" solutions spanning consultancy, research, CMC development, manufacturing, testing, clinical development, and strategic capital support.

Core Capabilities

Manufacturing & Process Development

• cGMP-compliant vaccine development and manufacturing with single-use solutions, process scale-up/scale-down, and process validation
• Cell bank preservation for cell lines, microbial cells, and biologics
• Cell culture process development and optimization, including medium optimization and seed preparation
• Plasmid DNA manufacturing at preclinical, clinical, and commercial scales with GMP standards
• Aseptic fill-and-finish services (first in Southeast Asia/ASEAN) with USP <1207> container-closure integrity testing and in-house autoclave sterilization
• Advanced formulation solutions for inhalation-based exosome delivery (nasal spray, nebulizer, dry powder)

Therapeutic Modalities

• Vaccine technologies (conventional inactivated, attenuated live, subunit, VLPs, DNA, self-amplifying RNA)
• Cell therapy including CAR-T cells, CAR-NK cells, and CAR-dendritic cells with process design through GMP manufacture
• Extracellular vesicles and exosome therapeutics
• Adherent cell line creation, banking, characterization, and storage
• Plasmid DNA for gene therapy applications

Preclinical & Clinical Services

• GLP Toxicology studies (material production and study oversight) aligned with investment milestones
• Preclinical to clinical testing for drug efficacy determination
• Lead optimization through commercialization support for advanced therapies
• MiniTide® 3D tissue culture platform as parallel to traditional 2D and organoid approaches

Strategic Services

• Strategic capital support and fundraising services
• Business development and enterprise support
• Venture ecosystem partnership

Therapeutic Areas

Serves diagnostics, therapeutics, vaccines, dermatology, dermocosmetics, cosmeceuticals, medical aesthetics, injectables, coatings, nutraceuticals, and cellular agriculture. Demonstrated commercial deployment in human and animal vaccines, dermocosmetics, cell-based nutrition, and clinical-grade stem cells and exosomes.