Sussex Research Laboratories Inc.

Overview

Sussex Research Laboratories Inc. is a specialized contract research organization (CRO) and contract development & manufacturing organization (CDMO) focused on glycoscience and carbohydrate chemistry. The company serves as a global leader in carbohydrate synthesis, glycan design, and glycoconjugate development.

Core Capabilities

Glycan Synthesis & Design

• Custom carbohydrate synthesis tailored to specific project requirements
• Expertise in scalable, cost-effective synthesis methods
• Specialization in GalNAc targeting ligands and hepatic/extra-hepatic drug delivery strategies
• Production of complex oligosaccharides and modified monosaccharide scaffolds

Glycopeptides & Peptides

• Over 20 years of glycopeptide synthesis expertise
• World's largest inventory of well-defined glycoamino acid building blocks
• Synthesis of tumor-associated carbohydrate antigens (TACA), PSGL-1 mimetics, and glycopolypeptides
• Capabilities in glycated, glycolipid, lipid, and macrocyclic peptides

Antibody Development

• Production of carbohydrate-based antigens for antibody screening and production
• Synthesis of glycan, glycopeptide, and glycolipid antigens with carrier protein conjugates (BSA, OVA, CRM, KLH)

Targeting Ligands

• Cell-specific carbohydrate ligands targeting ASGPR, Galectins, Siglecs, and other carbohydrate-binding protein receptors
• Lectin-mediated drug delivery solutions for challenging therapeutic molecules including RNA

Product Portfolio

• Extensive catalog of glycans, glycoamino acids, glycopeptides, glycan probes, and pharmaceutical standards
• Liquid Glycan Array (LiGA) platform for high-throughput glycan-based targeting discovery
• Neo-glycoprotein conjugates, lipopolysaccharides, and stable isotope standards

Service Model

Comprehensive project lifecycle support from initial consultation through post-delivery technical support, including:

• Feasibility assessments and bespoke proposals
• Research and development with regular progress updates
• Rigorous quality control and Certificate of Analysis documentation
• Connections to trusted network for pre-clinical and GMP manufacturing scale-up

Company Profile

• Founded: Over 25 years of industry experience
• Certifications: ISO 9001:2015 certified
• Client Base: 1000+ clients worldwide
• Manufacturing: Made in Canada with international recognition
• Applications: Vaccines, targeted drug delivery systems, therapeutic antibodies, diagnostics, and novel glycan-based therapeutics